Targeted Delivery of Curcumin to Polyethylene-Induced Osteolysis by Magnetically Guided Zoledronate-Anchored Poly Lactic-Co-Glycolic Acid Nanoparticles via Repressing NF-κB Signaling

• Үндсэн зохиолчид: Jingyi Li (Зохиогч), Chengcheng Niu (Зохиогч), Zichao Jiang (Зохиогч), Zhen Zhang (Зохиогч), Yixiao Pan (Зохиогч), Qiqi Xing (Зохиогч), Qi Guo (Зохиогч), Senbo An (Зохиогч), Yihe Hu (Зохиогч), Long Wang (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2020-12-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

Aseptic loosening induced by periprosthetic osteolysis (PPO) is the leading complication of total joint arthroplasty (TJA) and results in patients having to receive revision surgery. However, there is still no efficient drug to prevent or even slow the pathological process. Herein, we report novel d...