An epigenetic clock for human skeletal muscle

• Main Authors: Sarah Voisin (Author), Nicholas R. Harvey (Author), Larisa M. Haupt (Author), Lyn R. Griffiths (Author), Kevin J. Ashton (Author), Vernon G. Coffey (Author), Thomas M. Doering (Author), Jamie‐Lee M. Thompson (Author), Christian Benedict (Author), Jonathan Cedernaes (Author), Malene E. Lindholm (Author), Jeffrey M. Craig (Author), David S. Rowlands (Author), Adam P. Sharples (Author), Steve Horvath (Author), Nir Eynon (Author)
• Format: Book
• Published: Wiley, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ageing is associated with DNA methylation changes in all human tissues, and epigenetic markers can estimate chronological age based on DNA methylation patterns across tissues. However, the construction of the original pan‐tissue epigenetic clock did not include skeletal muscle sa...