Comparative study of anti-inflammatory, ulcerogenic and cytotoxic activities of racemate and S-ibuprofen
Ibuprofen is widely commercialized in racemic form. Although metabolic chiral inversion occurs through the conversion of R(-)-ibuprofen to S(+)-ibuprofen and the latter enantiomer is considered the active form, clinical trials involving the administration of a racemate to S-enantiomer dosage ratio o...
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São Paulo State University (UNESP),
2013-07-01T00:00:00Z.
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