RAGE and HMGB1 Expression in Orbital Tissue Microenvironment in Graves' Ophthalmopathy

• Main Authors: Dominika Łacheta (Author), Krzysztof B. Poślednik (Author), Katarzyna Czerwaty (Author), Nils Ludwig (Author), Marta Molińska-Glura (Author), Ireneusz Kantor (Author), Anna Jabłońska-Pawlak (Author), Piotr Miśkiewicz (Author), Alicja Głuszko (Author), Zygmunt Stopa (Author), Jacek Brzost (Author), Mirosław J. Szczepański (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Graves' ophthalmopathy (GO) is a chronic autoimmune inflammatory disorder involving orbital tissues. A receptor for advanced glycation end products (RAGE) and its ligand high mobility group box 1 (HMGB1) protein trigger inflammation and cell proliferation and are involved in the pathogenesis of...