Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis-1 with Everolimus: A Phase II, Open-Label, Single-Arm Trial

Treatment of Disfiguring Cutaneous Lesions in Neurofibromatosis-1 with Everolimus: A Phase II, Open-Label, Single-Arm Trial

Abstract Background Cutaneous neurofibromas cause disfigurement and discomfort in individuals with neurofibromatosis type 1 (NF-1). Methods The primary objective of this phase II, open-label, single-arm trial was to assess whether orally administered everolimus reduced the surface volume of cutaneou...

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Main Authors: John M. Slopis (Author), Octavio Arevalo (Author), Cynthia S. Bell (Author), Adelaide A. Hebert (Author), Hope Northrup (Author), Roy F. Riascos (Author), Joshua A. Samuels (Author), Keri C. Smith (Author), Patti Tate (Author), Mary Kay Koenig (Author)
Format: Book
Published: Adis, Springer Healthcare, 2018-10-01T00:00:00Z.
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