Intratracheal Administration of Itraconazole-Loaded Hyaluronated Glycerosomes as a Promising Nanoplatform for the Treatment of Lung Cancer: Formulation, Physiochemical, and In Vivo Distribution

• Main Authors: Sultan Aati (Author), Hanan O. Farouk (Author), Marwa H. Elkarmalawy (Author), Hanan Y. Aati (Author), Nahla Sameh Tolba (Author), Hossam M. Hassan (Author), Mostafa E. Rateb (Author), Doaa S. Hamad (Author)
• Format: Book
• Published: MDPI AG, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Itraconazole (ITZ) is an antiangiogenic agent recognized as a potent suppressor of endothelial cell growth that suppresses angiogenesis. Nevertheless, its exploitation is significantly restricted by its low bioavailability and systematic side effects. The objective of this study was to u...