Involvement of l-lactate in hippocampal dysfunction of type I diabetes

• Main Authors: Riho Kobayashi (Author), Junya Maruoka (Author), Hiroaki Norimoto (Author), Yuji Ikegaya (Author), Kazuhiko Kume (Author), Masahiro Ohsawa (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hippocampal neurons play a crucial role in memory formation. Accumulating evidence raises the possibility that hippocampal sharp-wave ripples (SW-Rs) are involved in memory consolidation. Here, we examined in an animal model of diabetes and found the amplitude of SW-Rs in diabetic mice were smaller...