The Self-Assembly Phenomenon of Poloxamers and Its Effect on the Dissolution of a Poorly Soluble Drug from Solid Dispersions Obtained by Solvent Methods

• Main Authors: Joanna Szafraniec (Author), Agata Antosik (Author), Justyna Knapik-Kowalczuk (Author), Krzysztof Chmiel (Author), Mateusz Kurek (Author), Karolina Gawlak (Author), Joanna Odrobińska (Author), Marian Paluch (Author), Renata Jachowicz (Author)
• Format: Book
• Published: MDPI AG, 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The self-assembly phenomenon of amphiphiles has attracted particular attention in recent years due to its wide range of applications. The formation of nanoassemblies able to solubilize sparingly water-soluble drugs was found to be a strategy to solve the problem of poor solubility of active pharmace...