Downregulation of DJ-1 Fails to Protect Mitochondrial Complex I Subunit NDUFS3 in the Testes and Contributes to the Asthenozoospermia

• Главные авторы: Yupeng Wang (Автор), Yi Sun (Автор), Xin Zhao (Автор), Renpei Yuan (Автор), Hui Jiang (Автор), Xiaoping Pu (Автор)
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• Опубликовано: Hindawi Limited, 2018-01-01T00:00:00Z.
• Предметы: article
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Asthenozoospermia (AS), an important cause of male infertility, is characterized by reduced sperm motility. Among the aetiologies of AS, inflammation seems to be the main cause. DJ-1, a conserved protein product of the PARK7 gene, is associated with male infertility and plays a role in oxidative str...