Synthesis and Biochemical Evaluation of Ethanoanthracenes and Related Compounds: Antiproliferative and Pro-Apoptotic Effects in Chronic Lymphocytic Leukemia (CLL)

• Main Authors: James P. McKeown (Author), Andrew J. Byrne (Author), Sandra A. Bright (Author), Clara E. Charleton (Author), Shubhangi Kandwal (Author), Ivan Čmelo (Author), Brendan Twamley (Author), Anthony M. McElligott (Author), Darren Fayne (Author), Niamh M. O'Boyle (Author), D. Clive Williams (Author), Mary J. Meegan (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic lymphocytic leukemia (CLL) is a malignancy of mature B cells, and it is the most frequent form of leukemia diagnosed in Western countries. It is characterized by the proliferation and accumulation of neoplastic B lymphocytes in the blood, lymph nodes, bone marrow and spleen. We report the sy...