D-Arg0-Bradykinin-Arg-Arg, a Latent Vasoactive Bradykinin B2 Receptor Agonist Metabolically Activated by Carboxypeptidases

• Hoofdauteurs: Hélène Bachelard (Auteur), Xavier Charest-Morin (Auteur), François Marceau (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2018-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

We previously reported hypotensive and vasodilator effects from C-terminally extended bradykinin (BK) sequences that behave as B2 receptor (B2R) agonists activated by vascular or plasma peptidases. D-Arg0-BK-Arg-Arg (r-BK-RR) is a novel prodrug peptide hypothetically activated by two catalytic cycle...