Twenty-four hour rhythmicity in mitochondrial network connectivity and mitochondrial respiration; a study in human skeletal muscle biopsies of young lean and older individuals with obesity

• Main Authors: Anne Gemmink (Author), Sabine Daemen (Author), Jakob Wefers (Author), Jan Hansen (Author), Dirk van Moorsel (Author), Puji Astuti (Author), Johanna A. Jorgensen (Author), Esther Kornips (Author), Gert Schaart (Author), Joris Hoeks (Author), Patrick Schrauwen (Author), Matthijs K.C. Hesselink (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Mitochondrial network dynamics may play role in metabolic homeostasis. Whether mitochondrial network dynamics are involved in adaptations to day-night fluctuations in energy supply and demand is unclear. Here we visualized and quantified the mitochondrial network morphology in human skele...