The Role of Hepatitis C Virus NS5A Region Mutation and SNP IL-28B of Host to Support Successful Pegylated Interferon and Ribavirin Treatment in Patients with HCV-HIV Coinfection: A Prospective Cohort Study

• Main Authors: Juferdy Kurniawan (Author), Rino A Gani (Author), Samsuridjal Djauzi (Author), Fera Ibrahim (Author), Kuntjoro Harimurti (Author), nafrialdi nafrialdi (Author), Suzanna Imannuel (Author)
• Format: Book
• Published: Interna Publishing, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: HIV infection in HCV-infected patients accelerates disease progression and reduces the success rate of Peg-IFN/RBV treatment. HCV mutation in NS5A-ISDR/PKR-BD region improved the outcome in HCV monoinfection treated with Peg-IFN/RBV. SNP-IL28B polymorphism is predicted to have an effect...