A model‐based approach leveraging in vitro data to support dose selection from the outset: A framework for bispecific antibodies in immuno‐oncology
Abstract FAP‐4‐1BBL is a bispecific antibody exerting 4‐1BB‐associated T‐cell activation only while simultaneously bound to the fibroblast activation protein (FAP) receptor, expressed on the surface of cancer‐associated fibroblasts. The trimeric complex formed when FAP‐4‐1BBL is simultaneously bound...
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Wiley,
2023-11-01T00:00:00Z.
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Internet
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A1234.567 |
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