Modulation of the mTOR Pathway by Curcumin in the Heart of Septic Mice

• Main Authors: Bruna A. C. Rattis (Author), Henrique L. Piva (Author), Andressa Duarte (Author), Frederico G. F. L. R. Gomes (Author), Janaína R. Lellis (Author), Danilo F. Soave (Author), Simone G. Ramos (Author), Antonio C. Tedesco (Author), Mara R. N. Celes (Author)
• Format: Book
• Published: MDPI AG, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

mTOR is a signaling pathway involved in cell survival, cell stress response, and protein synthesis that may be a key point in sepsis-induced cardiac dysfunction. Curcumin has been reported in vitro as an mTOR inhibitor compound; however, there are no studies demonstrating this effect in experimental...