Transporter-Mediated Cellular Distribution of Tyrosine Kinase Inhibitors as a Potential Resistance Mechanism in Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a hematologic neoplasm characterized by the expression of the BCR::ABL1 oncoprotein, a constitutively active tyrosine kinase, resulting in uncontrolled growth and proliferation of cells in the myeloid lineage. Targeted therapy using tyrosine kinase inhibitors (TKIs)...

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Bibliographic Details
Main Authors: Noor E. Verhagen (Author), Jan B. Koenderink (Author), Nicole M. A. Blijlevens (Author), Jeroen J. W. M. Janssen (Author), Frans G. M. Russel (Author)
Format: Book
Published: MDPI AG, 2023-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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