The Generation of an Artificial ATP Deficit Triggers Antibiotic Production in <i>Streptomyces lividans</i>

• Main Authors: Nicolas Seghezzi (Author), Emmanuelle Darbon (Author), Cécile Martel (Author), Michelle David (Author), Clara Lejeune (Author), Catherine Esnault (Author), Marie-Joelle Virolle (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In most <i>Streptomyces</i> species, antibiotic production is triggered in a condition of phosphate limitation, a condition that is known to be correlated with a low intracellular ATP content compared to growth in a condition of phosphate proficiency. This observation suggests that a low...