The proximal promoter region of <it>mTert </it>is sufficient to regulate telomerase activity in ES cells and transgenic animals

• Главные авторы: Pintado Belen (Автор), Nieto Marta (Автор), Maria Torres Juan (Автор), Relaño-Gines Aroa (Автор), Villa-Diaz Ana (Автор), Ramírez Miguel (Автор), Pericuesta Eva (Автор), Gutiérrez-Adán Alfonso (Автор)
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• Опубликовано: BMC, 2006-02-01T00:00:00Z.
• Предметы: article
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<p>Abstract</p> <p>Background</p> <p>The reverse transcriptase of telomerase (Tert) controls telomerase activity maintaining the end of linear chromosomes in eukaryotic cells. Telomerase function is highly active in undifferentiated multipotent stem cells, decreases wit...