MicroRNA-21 from bone marrow mesenchymal stem cell-derived extracellular vesicles targets TET1 to suppress KLF4 and alleviate rheumatoid arthritis

• Main Authors: Guo-Qing Li (Author), Yu-Xuan Fang (Author), Ying Liu (Author), Fan-Ru Meng (Author), Xia Wu (Author), Chun-Wang Zhang (Author), Yu Zhang (Author), Yan-Qing Liu (Author), Dan Liu (Author)
• Formato: Livro
• Publicado em: SAGE Publishing, 2021-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Accumulating evidence has demonstrated that bone marrow mesenchymal stem cells (BMSCs)-derived extracellular vesicles (EVs) can be used effectively to transfer drugs and biomolecules to target lesions. Meanwhile, BMSCs have been reported to be beneficial in the treatment of rheumatoid ar...