In Vitro Evaluation of Pharmacokinetic Properties of Selected Dual COX-2 and 5-LOX Inhibitors

• Main Authors: Jelena Bošković (Author), Vladimir Dobričić (Author), Jelena Savić (Author), Jelena Rupar (Author), Mara Aleksić (Author), Bojan Marković (Author), Olivera Čudina (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Evaluation of pharmacokinetic properties is a significant step at the early stages of drug development. In this study, an in vitro evaluation of the pharmacokinetic properties of five newly synthesized compounds was performed. These compounds belong to N-hydroxyurea and hydroxamic acid derivatives a...