Transient, flexible gene editing in zebrafish neutrophils and macrophages for determination of cell-autonomous functions

• मुख्य लेखकों: Abdulsalam I. Isiaku (लेखक), Zuobing Zhang (लेखक), Vahid Pazhakh (लेखक), Harriet R. Manley (लेखक), Ella R. Thompson (लेखक), Lucy C. Fox (लेखक), Satwica Yerneni (लेखक), Piers Blombery (लेखक), Graham J. Lieschke (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: The Company of Biologists, 2021-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Zebrafish are an important model for studying phagocyte function, but rigorous experimental systems to distinguish whether phagocyte-dependent effects are neutrophil or macrophage specific have been lacking. We have developed and validated transgenic lines that enable superior demonstration of cell-...