Use of preclinical models to identify markers of type 2 diabetes susceptibility and novel regulators of insulin secretion - A step towards precision medicine

• Main Authors: Bernard Thorens (Author), Ana Rodriguez (Author), Céline Cruciani-Guglielmacci (Author), Leonore Wigger (Author), Mark Ibberson (Author), Christophe Magnan (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Progression from pre-diabetes to type 2 diabetes (T2D) and from T2D to insulin requirement proceeds at very heterogenous rates among patient populations, and the risk of developing different types of secondary complications is also different between patients. The diagnosis of pre-diabete...