In vivo Pharmacokinetic Drug-Drug Interaction Studies Between Fedratinib and Antifungal Agents Based on a Newly Developed and Validated UPLC/MS-MS Method

• Главные авторы: Congrong Tang (Автор), Xiaohui Niu (Автор), Lu Shi (Автор), Huidan Zhu (Автор), Guanyang Lin (Автор), Ren-ai Xu (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

In the current research experiment, a sensitive, precise and rapid bioanalytical approach involving the detection of fedratinib concentrations in rat plasma by ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) technique was optimized and established, and it was employed t...