Metformin Alleviates LPS-Induced Acute Lung Injury by Regulating the SIRT1/NF-κB/NLRP3 Pathway and Inhibiting Endothelial Cell Pyroptosis

• Egile Nagusiak: Yunqian Zhang (Egilea), Hui Zhang (Egilea), Siyuan Li (Egilea), Kai Huang (Egilea), Lai Jiang (Egilea), Yan Wang (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-07-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Acute respiratory distress syndrome (ARDS), a devastating complication of numerous conditions, is often associated with high mortality. It is well known that endothelial cell (EC) damage and inflammation are vital processes in the pathogenesis of ARDS. Nevertheless, the mechanisms of EC damage are l...