Triptolide Alleviates Oxidized LDL-Induced Endothelial Inflammation by Attenuating the Oxidative Stress-Mediated Nuclear Factor-Kappa B Pathway

• Auteurs principaux: Shiyu Zhang, MD (Auteur), Shiyang Xie, MD (Auteur), Yuan Gao, MD (Auteur), Youping Wang, MD, PhD (Auteur)
• Format: Livre
• Publié: Elsevier, 2022-01-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background: Endothelial inflammation triggered by oxidized LDL (ox-LDL) is a crucial mechanism involved in atherosclerosis. Triptolide (TP), a primary active ingredient of the traditional Chinese medicine Tripterygium wilfordii Hook F, possesses antioxidant and anti-inflammatory properties in vivo....