Preparation of pentagamaboronon-0 and its fructose and sorbitol complexes as boron carrier for boron neutron capture therapy (BNCT) application

• Main Authors: Ratna Asmah Susidarti (Author), Rohmad Yudi Utomo (Author), Lailatul Qodria (Author), Ratna Dwi Ramadani (Author), Youichiro Ohta (Author), Yoshihide Hattori (Author), Mitsunori Kirihata (Author), Edy Meiyanto (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Development of specific and selective boron carriers is indispensable for boron neutron capture therapy (BNCT) application. Pentagamaboronon-0 (PGB-0) is a promising candidate as boron carrier compound due to the low but selective cytotoxicity in breast cancer cells. Formerly we reported synthesis o...