Palmitoylethanolamide Counteracts Enteric Inflammation and Bowel Motor Dysfunctions in a Mouse Model of Alzheimer's Disease

• Main Authors: Vanessa D'Antongiovanni (Author), Carolina Pellegrini (Author), Luca Antonioli (Author), Laura Benvenuti (Author), Clelia Di Salvo (Author), Lorenzo Flori (Author), Rebecca Piccarducci (Author), Simona Daniele (Author), Alma Martelli (Author), Vincenzo Calderone (Author), Claudia Martini (Author), Matteo Fornai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Palmitoylethanolamide (PEA), an endogenous lipid mediator, is emerging as a promising pharmacological agent in multiple neurodegenerative disorders for its anti-inflammatory and neuroprotective properties. However, its effects on enteric inflammation and colonic dysmotility associated with Alzheimer...