Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation

• Main Authors: Manoj K. Gupta (Author), Dario F. De Jesus (Author), Sevim Kahraman (Author), Ivan A. Valdez (Author), Farnaz Shamsi (Author), Lian Yi (Author), Adam C. Swensen (Author), Yu-Hua Tseng (Author), Wei-Jun Qian (Author), Rohit N. Kulkarni (Author)
• Format: Book
• Published: Elsevier, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: Insulin receptor (IR)-mediated signaling is involved in the regulation of pluripotent stem cells; however, its direct effects on regulating the maintenance of pluripotency and lineage development are not fully understood. The main objective of this study is to understand the role of IR s...