Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation

• Principais autores: Manoj K. Gupta (Autor), Dario F. De Jesus (Autor), Sevim Kahraman (Autor), Ivan A. Valdez (Autor), Farnaz Shamsi (Autor), Lian Yi (Autor), Adam C. Swensen (Autor), Yu-Hua Tseng (Autor), Wei-Jun Qian (Autor), Rohit N. Kulkarni (Autor)
• Formato: Livro
• Publicado em: Elsevier, 2018-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Objectives: Insulin receptor (IR)-mediated signaling is involved in the regulation of pluripotent stem cells; however, its direct effects on regulating the maintenance of pluripotency and lineage development are not fully understood. The main objective of this study is to understand the role of IR s...