Anti-atherogenic Effects of a New Thienylacylhydrazone Derivative, LASSBio-788, in Rats Fed a Hypercholesterolemic Diet

• Main Authors: Nadia Alice Vieira da Motta (Author), Arthur Eugen Kümmerle (Author), Elisabeth Marostica (Author), Caroline Fernandes dos Santos (Author), Carlos Alberto Manssour Fraga (Author), Eliezer Jesus Barreiro (Author), Ana Luisa Palhares de Miranda (Author), Fernanda Carla Ferreira de Brito (Author)
• Format: Book
• Published: Elsevier, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The compound LASSBio-788 (N-Allyl (2-thienylidene) 3,4-methylenedioxybenzoylhydrazine) is a thienylacylhydrazone derivative shown to have antiplatelet, vasodilatory, and anti-inflammatory properties in vitro. We hypothesize that LASSBio-788 may exert beneficial effects on atherosclerosis. Male wista...