A novel role for GalNAc-T2 dependent glycosylation in energy homeostasis

• Main Authors: Cristy R.C. Verzijl (Author), Federico Oldoni (Author), Natalia Loaiza (Author), Justina C. Wolters (Author), Antoine Rimbert (Author), E. Tian (Author), Weiming Yang (Author), Dicky Struik (Author), Marieke Smit (Author), Niels J. Kloosterhuis (Author), Amy J. Fernandez (Author), Nadine L. Samara (Author), Kelly G. Ten Hagen (Author), Kruti Dalal (Author), Aliona Chernish (Author), Peggy McCluggage (Author), Lawrence A. Tabak (Author), Johan W. Jonker (Author), Jan Albert Kuivenhoven (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: GALNT2, encoding polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2), was initially discovered as a regulator of high-density lipoprotein metabolism. GalNAc-T2 is known to exert these effects through post-translational modification, i.e., O-linked glycosylation of secreted protein...