High fat diet modulates Trypanosoma cruzi infection associated myocarditis.

• Main Authors: Fnu Nagajyothi (Author), Louis M Weiss (Author), Dazhi Zhao (Author), Wade Koba (Author), Linda A Jelicks (Author), Min-Hui Cui (Author), Stephen M Factor (Author), Philipp E Scherer (Author), Herbert B Tanowitz (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trypanosoma cruzi, the causative agent of Chagas disease, has high affinity for lipoproteins and adipose tissue. Infection results in myocarditis, fat loss and alterations in lipid homeostasis. This study was aimed at analyzing the effect of high fat diet (HFD) on regulating acute T. cruzi infection...