QT PRODACT: In Vivo QT Assay in Anesthetized Dog for Detecting the Potential for QT Interval Prolongation by Human Pharmaceuticals

The purpose of this study was to assess the utility of the isoflurane-anesthetized dog model for detecting the potential for QT interval prolongation by human pharmaceuticals. The effects of 10 positive compounds with torsadogenic potential, 8 negative compounds with little torsadogenic potential, a...

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Bibliographic Details
Main Authors: Hiroyuki Tashibu (Author), Hiroyasu Miyazaki (Author), Kumiko Aoki (Author), Yasuki Akie (Author), Keiji Yamamoto (Author)
Format: Book
Published: Elsevier, 2005-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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