High-expression of ROCK1 modulates the apoptosis of lens epithelial cells in age-related cataracts by targeting p53 gene

• Main Authors: Shanshan Hu (Author), Dongmei Su (Author), Lei Sun (Author), Zhongying Wang (Author), Lina Guan (Author), Shanhe Liu (Author), Baowen Zhao (Author), Yong Liu (Author), Cuige Shi (Author), Jianbo Yu (Author), Xu Ma (Author)
• Format: Book
• Published: BMC, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Age-related cataract (ARC) is a serious visual impairment disease, and its pathogenesis is unclear. This article aims to investigate the role of ROCK1 in the apoptosis of lens epithelial cells (LECs) in age-related cataracts. Methods We collect anterior capsule samples from norma...