Metformin reduces ovarian ischemia reperfusion injury in rats by improving oxidative/nitrosative stress

• Main Authors: Mustafa Demir (Author), Bulent Yilmaz (Author), Senol Kalyoncu (Author), Meltem Tuncer (Author), Zehra Bozdag (Author), Onur Ince (Author), Mehmet Akif Bozdayi (Author), Hasan Ulusal (Author), Seyithan Taysi (Author)
• Format: Book
• Published: Elsevier, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To assess the preventive role of metformin on rat ovarian ischemia reperfusion injury. Materials and methods: Forty rats were divided equally into five groups; Group 1: sham, Group 2: surgical control with 3-hr torsion and detorsion, Group 3: 50 mg/kg p.o. metformin 30 min before 3-hr tor...