Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy

• Hoofdauteurs: Kamila Butowska (Auteur), Xuexiang Han (Auteur), Ningqiang Gong (Auteur), Rakan El-Mayta (Auteur), Rebecca M. Haley (Auteur), Lulu Xue (Auteur), Wenqun Zhong (Auteur), Wei Guo (Auteur), Karin Wang (Auteur), Michael J. Mitchell (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2023-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Evasion of apoptosis is a hallmark of cancer, attributed in part to overexpression of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2). In a variety of cancer types, including lymphoma, Bcl-2 is overexpressed. Therapeutic targeting of Bcl-2 has demonstrated efficacy in the clinic and is the subj...