Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis.

• मुख्य लेखकों: Tineke Lauwaet (लेखक), Yukiko Miyamoto (लेखक), Sozaburo Ihara (लेखक), Christine Le (लेखक), Jarosław Kalisiak (लेखक), Keith A Korthals (लेखक), Majid Ghassemian (लेखक), Diane K Smith (लेखक), K Barry Sharpless (लेखक), Valery V Fokin (लेखक), Lars Eckmann (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Public Library of Science (PLoS), 2020-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Giardiasis and other protozoan infections are major worldwide causes of morbidity and mortality, yet development of new antimicrobial agents with improved efficacy and ability to override increasingly common drug resistance remains a major challenge. Antimicrobial drug development typically proceeds...