Discovery of a fragment hit compound targeting D-Ala:D-Ala ligase of bacterial peptidoglycan biosynthesis

Bacterial resistance is an increasing threat to healthcare systems, highlighting the need for discovering new antibacterial agents. An established technique, fragment-based drug discovery, was used to target a bacterial enzyme Ddl involved in the biosynthesis of peptidoglycan. We assembled general a...

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Bibliographic Details
Main Authors: Matic Proj (Author), Martina Hrast (Author), Gregor Bajc (Author), Rok Frlan (Author), Anže Meden (Author), Matej Butala (Author), Stanislav Gobec (Author)
Format: Book
Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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