Alteration in Marrow Stromal Microenvironment and Apoptosis Mechanisms Involved in Aplastic Anemia: An Animal Model to Study the Possible Disease Pathology

• Main Authors: Sumanta Chatterjee (Author), Ranjan Kumar Dutta (Author), Pratima Basak (Author), Prosun Das (Author), Madhurima Das (Author), Jacintha Archana Pereira (Author), Malay Chaklader (Author), Samaresh Chaudhuri (Author), Sujata Law (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aplastic anemia (AA) is a heterogeneous disorder of bone marrow failure syndrome. Suggested mechanisms include a primary stem cell deficiency or defect, a secondary stem cell defect due to abnormal regulation between cell death and differentiation, or a deficient microenvironment. In this study, we...