Adenine: an important drug scaffold for the design of antiviral agents

• Egile Nagusiak: Changyuan Wang (Egilea), Zhendong Song (Egilea), Haiqing Yu (Egilea), Kexin Liu (Egilea), Xiaodong Ma (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2015-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Adenine derivatives, in particular the scaffold bearing the acyclic nucleoside phosphonates (ANPS), possess significant antiviral and cytostatic activity. Till now, several effective adenine derivatives have been marketed for the treatment of HIV, HBV, CMV and other virus-infected diseases. These co...