Unveiling post-MIS-N cardiomyopathy by longitudinal multimodality global cardiac assessment from neonatal insult to 16-month follow-up

A full-term male neonate presented on the 11th day of life with late-onset multisystem inflammatory syndrome-neonate (MIS-N) (cardioneurological compromise). Immediate anti-inflammatory modulation led to a gradual recovery of neurological and coronary lesions. However, temporal evaluation unmasked s...

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Main Authors: Maitri Chaudhuri (Author), Munesh Tomar (Author), Balasubramanyam Shankar (Author)
Format: Book
Published: Wolters Kluwer Medknow Publications, 2023-04-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Maitri Chaudhuri  |e author 
700 1 0 |a Munesh Tomar  |e author 
700 1 0 |a Balasubramanyam Shankar  |e author 
245 0 0 |a Unveiling post-MIS-N cardiomyopathy by longitudinal multimodality global cardiac assessment from neonatal insult to 16-month follow-up 
260 |b Wolters Kluwer Medknow Publications,   |c 2023-04-01T00:00:00Z. 
500 |a 0974-2069 
500 |a 0974-5149 
500 |a 10.4103/apc.apc_114_23 
520 |a A full-term male neonate presented on the 11th day of life with late-onset multisystem inflammatory syndrome-neonate (MIS-N) (cardioneurological compromise). Immediate anti-inflammatory modulation led to a gradual recovery of neurological and coronary lesions. However, temporal evaluation unmasked silent myocardial dysfunction in echocardiography validated further by elevated biomarkers, myocardial fibrosis in cardiac magnetic resonance imaging, and abnormal strain study persisting till 16 months of follow-up. This revealed a hitherto unknown and rare progression of MIS-N into dilated cardiomyopathy. 
546 |a EN 
690 |a cardiac magnetic resonance imaging 
690 |a dilated cardiomyopathy 
690 |a multisystem inflammatory syndrome-neonate 
690 |a strain imaging 
690 |a Medicine 
690 |a R 
690 |a Pediatrics 
690 |a RJ1-570 
690 |a Diseases of the circulatory (Cardiovascular) system 
690 |a RC666-701 
655 7 |a article  |2 local 
786 0 |n Annals of Pediatric Cardiology, Vol 16, Iss 6, Pp 463-467 (2023) 
787 0 |n https://journals.lww.com/10.4103/apc.apc_114_23 
787 0 |n https://doaj.org/toc/0974-2069 
787 0 |n https://doaj.org/toc/0974-5149 
856 4 1 |u https://doaj.org/article/ed56a5a0d84d42dbb5a8f504ac7a69f9  |z Connect to this object online.