Preparation and Bioevaluation of Novel ^99mTc-Labeled Complexes with a 2-Nitroimidazole HYNIC Derivative for Imaging Tumor Hypoxia

• Главные авторы: Qing Ruan (Автор), Qianqian Gan (Автор), Xuran Zhang (Автор), Si'an Fang (Автор), Junbo Zhang (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2021-02-01T00:00:00Z.
• Предметы: article
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To develop novel ^99mTc-labeled single-photon emission computed tomography (SPECT) radiotracers for imaging hypoxia, a novel HYNICNM ligand (6-hydrazinonicotinamide (HYNIC) 2-nitroimidazole derivative) was designed and synthesized. It was radiolabeled with technetium-99m using...