Cannabinoid Receptor Activation Disrupts the Internal Structure of Hippocampal Sharp Wave-Ripple Complexes

• Ngā kaituhi matua: Yi Sun (Author), Hiroaki Norimoto (Author), Xiao-Ping Pu (Author), Norio Matsuki (Author), Yuji Ikegaya (Author)
• Hōputu: Pukapuka
• I whakaputaina: Elsevier, 2012-01-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Cannabinoid agonists impair hippocampus-dependent learning and memory. Using mouse hippocampal slice preparations, we examined the effect of anandamide, an endogenous cannabinoid, on sharp wave-ripple (SW-R) complexes, which are believed to mediate memory consolidation during slow-wave sleep or beha...