Leukotriene D4 Stimulates the Migration but Not Proliferation of Endothelial Cells Mediated by the Cysteinyl Leukotriene CysLT1 Receptor via the Extracellular Signal-Regulated Kinase Pathway

• Main Authors: Yu-Mei Yuan (Author), San-Hua Fang (Author), Xiao-Dong Qian (Author), Li-Ying Liu (Author), Li-Hua Xu (Author), Wen-Zhen Shi (Author), Li-Hui Zhang (Author), Yun-Bi Lu (Author), Wei-Ping Zhang (Author), Er-Qing Wei (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The actions of cysteinyl leukotrienes (CysLTs) are mediated by activating CysLT receptors, CysLT1, and CysLT2. The CysLT1 receptor mediates vascular responses to CysLTs; however, its effect on the proliferation and migration of endothelial cells is not clarified. To determine this effect, we observe...