Cost-utility analysis of genetic screening in families of patients with germline <it>MUTYH </it>mutations

• मुख्य लेखकों: Vasen Hans FA (लेखक), Hes Frederik J (लेखक), Nielsen Maartje (लेखक), van den Hout Wilbert B (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2007-07-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>MUTYH associated polyposis (MAP) is an autosomal recessive inherited disorder. Carriers of bi-allelic <it>MUTYH </it>germline mutations have a risk of approximately 60% to develop colorectal carcinoma (CRC). In the genera...