Pirfenidone-induced liver injury, a case report of a rare idiosyncratic reaction

• Main Authors: Florent Fortunati (Author), Antoine Froidure (Author), Pamela Baldin (Author), Yves Horsmans (Author), Nicolas Lanthier (Author), Géraldine Dahlqvist (Author), Bénédicte Delire (Author)
• Format: Book
• Published: SAGE Publishing, 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nearly all medications carry the risk of drug-induced liver injury (DILI). Idiosyncratic reactions are rare and poorly predictable, and the mechanisms are not always well understood. Pirfenidone is an oral antifibrotic drug used to treat idiopathic pulmonary fibrosis. While elevation of liver enzyme...