Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines

• Main Authors: Jarjanazi Hamdi (Author), Ibrahim-zada Irada (Author), Eng Lawson (Author), Savas Sevtap (Author), Meschian Mehran (Author), Pritchard Kathleen I (Author), Ozcelik Hilmi (Author)
• Format: Book
• Published: BMC, 2011-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Paclitaxel is a microtubule-stabilizing drug that has been commonly used in treating cancer. Due to genetic heterogeneity within patient populations, therapeutic response rates often vary. Here we used the NCI60 panel to identify SNP...