Modulation of oxazolone-induced hypersensitivity in mice by selective PDE inhibitors

• मुख्य लेखकों: I. Moodley (लेखक), Y. Sotsios (लेखक), B. Bertin (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 1995-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The effects of PDE inhibitors on oxazolone-induced contact hypersensitivity (CS) were studied in mice. Rolipram, Ro 20-1724 and theophylline dose dependently inhibited CS but none caused >53% inhibition. ED30 values at 24 h before challenge for rolipram, Ro 20-1724 and theophylline were 2.1, 5.4...