AAV-CRISPR/Cas9 Gene Editing Preserves Long-Term Vision in the P23H Rat Model of Autosomal Dominant Retinitis Pigmentosa

• Główni autorzy: Saba Shahin (Autor), Hui Xu (Autor), Bin Lu (Autor), Augustus Mercado (Autor), Melissa K. Jones (Autor), Benjamin Bakondi (Autor), Shaomei Wang (Autor)
• Format: Książka
• Wydane: MDPI AG, 2022-04-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Retinitis pigmentosa (RP) consists of a group of inherited, retinal degenerative disorders and is characterized by progressive loss of rod photoreceptors and eventual degeneration of cones in advanced stages, resulting in vision loss or blindness. Gene therapy has been effective in treating autosoma...