Simulation of metabolism-based herb-drug interaction: towards safe and efficacious use of NIPRD-AM1

• Main Authors: Bulus Adzu (Author), Kudirat Bola Mustapha (Author), Collen Masimirembwa (Author), Obiageri Obodozie (Author), Rukaiyatu Abdullahi Kirim (Author), Karniyus Shingu Gamaniel (Author)
• Format: Book
• Published: Mashhad University of Medical Sciences, 2013-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: To evaluate the effect of NIPRD-AM1 on CYP3A4 in order to generate clinically significant data for its safe and efficacious use. Materials and Methods: NIPRD-AM1 is a phytomedicine developed from aqueous root extracts of Nauclea latifolia Smith (Rubiaceae) for the treatment of uncomplicat...